Medicinal Chemistry Expertise

Califiabio

CALIFIA BIO

Hit-to-Lead Services and Capabilities

Target guided compound design

Structure-based modeling

In silico screening and docking

In silico physicochemical and ADME property calculations

Hit re-synthesis and confirmation

Scaffold scale-ups

Rapid SAR confirmation for series

Patent busting/Fast follower design

Lead Optimization


a

Functional activity

Potency/in vivo efficacy

Oral bioavailability

CNS penetration

Solubility and stability

ADME properties

Toxicological profiles and specificity

 

Our areas of expertise

 

 

© 2011 Calfia Bio Inc.